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There are several mechanisms involved

Dopamine efflux by MPTP and hydroxyl radical generation

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Magnesium deficiency is a known trigger for tension-type headaches and migraines

Hashimotos thyroiditis, a chronic autoimmune condition characterized by lymphocytic infiltration of the thyroid gland and the presence of elevated antithyroid antibodies such as thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb), remains the primary cause of hypothyroidism in iodine-sufficient populations (Liu et al., 2022)