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Serotonin transporters increased after just four weeks of hormone therapy [] The study has shown that testosterone increases the potential binding sites for commonly prescribed antidepressants such as SSRIs in the brain and therefore provides major insights into how sex hormones affect the human brain and gender differences in psychiatric illnesses, says Siegfried Kasper, Head of the University Department of Psychiatry and Psychotherapy at the MedUni Vienna

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Statistical significance was tested by Oneway ANOVA