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Introduction With the advancement of the social economy and alterations in lifestyle patterns, chronic metabolic disorders like obesity and diabetes have emerged as major public health issues (1, 2)

This peptide is found in human plasma, saliva, and urine and has been extensively studied for its various biological activities, particularly its role in skin health, wound healing, and anti-aging

Their significance in the mechanism of breast cancer tumorigenesis is highlighted by their proposal as potential biomarkers of its prognosis (discussed in Section 5)

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In February 2021, the researchers published the findings from their trial in The New England Journal of Medicine, showing that patients using semaglutide lost almost 15% of their body weight, on average, compared with 2.4% among patients who got the placebo