what hormones does glp 1 affect Science Behind GIP and Glucagon Receptor Agonists for Obesity Research | News & Announcements GLP-1 And Health: Beyond Weight

At this stage, the doses are large enough that syringe readability is not an issue

The clinical trial data (OASIS 4, NEJM 2025) showed an average body weight loss of 16.6% at 64 weeks

GLP-1 brands have been steadily expanding their reach through new indications, with Ozempic and Wegovy adding cardiovascular risk reduction in 2020 and 2024 respectively, and Zepbound adding obstructive sleep apnea in 2024

This could impact their mental health if not adequately addressed

What to set as your healthy expectation if youre starting GLP-1 If you want a clean, realistic way to frame it: First 12 months: appetite shifts + early weight movement By ~4 months: more noticeable progress (if dose escalation is tolerated) (Source: European Medicines Agency (EMA)) By ~1216 months: many eligible adults land in the 1015% weight-loss range (some higher, some lower) (Source: New England Journal of Medicine) Best outcomes happen when you protect muscle (protein + strength) and build routines you can sustain.