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Additionally, it has shown promise in reducing cortisol (stress hormone), supporting growth hormone (GH) secretion, and modulating pain perception

The same relationship is seen in weight regain after lifestyle-only (diet and exercise) weight loss

Because progressive loss of -cell insulin secretory capacity is associated with worsening hyperglycemia, targeting intrinsic -cell activity is considered essential in T2D management

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The genetics conversation gets more relevant in the off-label context, not less, because the diagnostic anchors that drive on-label prescribing are absent and something has to fill that decision-support gap