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Treatment typically begins with a low starter dose (0.25 mg weekly for 4 weeks), followed by gradual increases (0.5 mg, then up to 12 mg weekly for Ozempic, or up to 2.4 mg for Wegovy), depending on tolerability and clinical response

130 Fasting or intake of an FMD can cause various metabolic changes, including alterations in the systemic levels of hormones and growth factors such as insulin, glucagon, growth hormone, IGF-1, glucocorticoids or adrenaline

Rehman T, Shabbir MA, Inam-Ur-Raheem M, Manzoor MF, Ahmad N, Liu ZW, et al

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A suboptimal intake of the essential amino acids increases the body's need for the non-essential amino acids either through diet or supplementation