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A previous study indicated that treatment with the GLP-1 agonist liraglutide (subcutaneously at a dose gradually titrated from 0.6 to 3 mg) in bipolar and mood disorder depression patients could result in an improvement in cognitive function and an alleviation of depressive pathological symptoms (Cuomo et al., 2018)

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People taking metformin alongside tirzepatide for diabetes management are at increased risk of B12 deficiency because metformin impairs B12 absorption