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Measurements of associated genes by real-time PCR The total RNA was extracted from the skin of the KO and control groups using TRIzol reagent (Thermo Fisher Scientific, ShangHai)

In some cases, it can reduce healing time by 30-50%

Reduced stress: Whether because of a combination of the above benefits, or because of affects of the Vitamin B12 injection itself is unclear, patients have reported a significant decline in stress after receiving Vitamin B12 injections

The metabolic profiling revealed that AOD9604 undergoes rapid proteolytic degradation in serum, generating a series of predictable fragment peptides

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