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Side Effect 5: Systemic Effects Systemic reactions may include fatigue, anxiety, and numbness in extremities

This is also the future direction of ferroptosis research

McDonald M, Hertz RP, Unger AN, Lustik MB

In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

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