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However, these subjective findings are contradicted by EEG analyses, which in contrast revealed no apparent sedation in the classic pharmacologic way

16 It is widely expressed in metabolically active tissues, including the liver, heart, skeletal muscle, and adipose tissue, 2325 and is involved in diverse cellular processes such as metabolic homeostasis, antioxidant defense, autophagy, inflammation, and energy balance

The most notable effect on dark circles and bags is collagen production

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Combination of ursodeoxycholic acid and glycyrrhizic acid (Phosphogliv URSO) in the treatment of nonalcoholic fatty liver disease: results of a multicenter randomized clinical trial on efficacy and safety