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More interestingly, many users maintain at least some of their changed habits even after stopping treatment

Studies have shown it increases IGF-1 levels by up to 60% and promotes lean mass gains in older men ( Source: Nass et al., J Clin Endocrinol Metab, 2008

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These points highlight the importance of carefully evaluating a patients medical and psychiatric background before initiating GLP-1 RA therapy and point to an urgent need for well-designed prospective clinical studies to clarify the mental health effects of these drugs in individuals with obesity

Patients with pre-existing gastroparesis, gastric ulcers, or severe reflux disease should discuss GLP-1 candidacy carefully with their physician