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4 Conclusion and outlook This article reviews the molecular mechanisms of ferroptosis-induced osteoporosis, summarizes the signaling pathways through which ferroptosis affects bone metabolism, and focuses on the three-dimensional regulatory network of iron metabolism disorder, lipid peroxidation and bone homeostasis imbalance

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2017;12(6):e0179538

This reduction in T3 can manifest as hypothyroid symptoms such as fatigue, weight gain, and cold intolerance, even though T4 levels may appear normal

It is possible that studies with negative or non-significant results were less likely to be published, which could lead to an overestimation of treatment effects