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While a typical oral supplement might deliver 200-1,000mg of vitamin C with limited absorption, high-dose IV therapy can safely administer 10,000-50,000mg (10-50 grams) in a single session

544 In addition, emerging targets such as IL-36 pathway inhibitors promote Treg cell proliferation by neutralizing the proinflammatory effects of IL-36, and TLR4/MyD88 small molecule inhibitors provide a new way of treating UC by modulating innate immune hyperactivation triggered by colony dysregulation

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