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Intestinal barrier function in morbid obesity: results of a prospective study on the effect of sleeve gastrectomy

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A microbiome-based random forest classifier was therefore constructed to predict the TMAO producer phenotype (AUROC = 0.81) which was then validated with an external cohort (AUROC = 0.80)

They are not illegal to buy or own, but they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing