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2.2 Inclusion criteria: literature screening Two review authors (WS and LT) independently screened the titles and abstracts of the initially identified studies

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TLR4 is one such PRR that detects damage-associated molecular patterns (DAMPs) created by stressed and dying cells and pathogen-associated molecular patterns (PAMPs) like bacterial lipopolysaccharide (LPS) (Guo et al., 2022

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