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This compound is supplied as a research-grade preparation intended for controlled laboratory use in analytical, biochemical, and in-vitro research applications
A frequently cited 1992 study found that a single 3-gram dose of oral glutathione did not increase circulating levels in humans, and this finding was used to dismiss the entire category
doi: 10.1155/2014/169216
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Alterations in the normal function of excitatory amino acid carrier 1 affect cysteine transport and GSH synthesis impairing zinc homeostasis (the thiol group of GSH can function as a principal Zn 2+ chelator for the maintenance of Zn 2+ homeostasis in neurons) and oxidative stress, enhancing susceptibility to ischemia-induced neuronal cell death in the hippocampus (162164)
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