The selected final sequences listed in Supplementary Table 6 were analysed in terms of the total number of mutations from wild-type and predicted potencies
Interestingly, estrogen receptors ER and ER are located in the axons and synaptic terminals of pre-synaptic cells and also in the dendritic spines (structures crucial for synaptic transmission) of post-synaptic cells (McEwen and Milner, 2007), indicating a role in local regulation of synapsis instead of exerting an effect at nuclear transcription (Zarate et al., 2017)
The high selectivity of oxamic hydrazide toward CSE was rationalized based on the crystal structure of the rat CSE complex with this inhibitor
Ozempic face refers to the gaunt, aged facial appearance that occurs when GLP-1 weight loss medications cause rapid fat loss throughout the body, including the face
DATA AND SOFTWARE AVAILABILITY The RNA-Seq data obtained in this study has been uploaded to NCBI GEO datasets, under accession number GSE94395 ( The software to analyze the data is available at Supplementary Material Highlights