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This homeostatic modulation, rather than directional stimulation, suggests a fundamentally different mechanism than most vasodilators

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- continue to regularly monitor B12 status every 3-6 months to ensure levels stabilize well within acceptable range

Because the body stores about 1,000 to 2,000 times as much as the typical daily intake of the vitamin, it can take several years to develop clinical symptoms of vitamin B12 deficiency