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However, strong inhibitors of CYP3A (e.g., itraconazole, clarithromycin) may increase the plasma concentrations of amlodipine to a greater extent [see Drug Interactions (7)]

This rebound effect reflects the return of increased appetite, normalization of gastric emptying, and loss of the medication's metabolic benefits rather than any unique withdrawal phenomenon

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Advances in biomarkers for the early diagnosis of prostate cancer