average weight loss glp-1 A diabetes drug. Then a weight-loss drug. Then a global blockbuster. Here's how GLP-1s went from helping manage blood sugar to becoming one of medicine's biggest stories. [GLP-1, Ozempic, Wegovy, Mounjaro, diabetes GLP-1 vs Bariatric Surgery Study:

DOI: 10.1038/s41467-017-01114-1 Formulation strategies for therapeutic peptide stability pH, ionic strength, co-solvency

Thus, there is a growing need to implement innovative strategies for assessing drug efficacy more rapidly and with greater personalization, highlighting the urgent need for advanced in vitro models, including the immune-competent, multi-tissue RA-on-chip platforms, capable of replicating the complex interplay between immune cells and joint-resident stromal components (49, 94, 194, 195)

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[DOI] [PubMed] [Google Scholar] 92.Wakabayashi K.T., Baindur A.N., Feja M., Suarez M., Chen K., Bernosky-Smith K., Bass C.E