First, a special amino acid in the enzymes active siteoften selenocysteine in key isoformsgets oxidized by the peroxide, forming an intermediate called selenenic acid
Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases
So now what's happened is that now everybody's doing these gene testings And finally got hey, do I have gene mutation where my body cannot produce gluothione if the answer is yes Then I don't care how much product you take from outside sources, the body is not [00:16:00] able to effectively produce glutathione correctly all the time
You can read more about this here: A review of adverse effects from IV glutathione
Zhang Y, Wang L, He J, Wang H, Xin W, Wang H, Zhang J (2024) Antioxidation and hepatoprotection of selenium mycelium polysaccharides against alcoholic liver diseases from the cultivated Morel mushroom Morchella esculenta (Ascomycota)