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Semaglutide is the GLP-1 medication ingredient used in FDA-approved products such as Ozempic and Wegovy, and it should only be used with licensed-provider oversight

Food & Drug Administration (FDA) determined that the shortage of the tirzepatide injection, a glucagon-like peptide 1 (GLP-1) medication, has been resolved and removed from the FDAs shortage list, see our prior blog GLP-1 Drugs: FDA Removes Lillys Zepbound and Mounjaro (tirzepatide injection) from its Drug Shortage List, on October 8, 2024, the Outsourcing Facilities Association (OFA) a trade association representing FDA-registered 503B outsourcing facilities filed a lawsuit against the FDA relating to the agencys removal of tirzepatide, from the FDAs drug shortage list

To be clear, the evidence linking GLP-1 agonists to gastroparesis and pancreatitis is suggestive, not definitive

This metabolite accumulates when B12 is functionally inadequate

But what you do with those changes, how you fill the smaller plate, what nutrients you prioritize when you are eating less overall, that determines whether you come out of this process leaner and healthier or just lighter on the scale with less muscle to show for it