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In triple-negative (TN)BC, erianin exerts anticancer effects through a dual mechanism: Erianin activates the mitochondrial apoptosis pathway and inhibits PI3K/Akt signal transduction (46,47) and regulates the cholesterol metabolism pathway by targeting sarcoma gene, which significantly inhibits cancer proliferation and migration (47,48)

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Research indicates that altered neuroplasticity and epigenetic mechanisms, including histone modifications, maintain these neuroadaptations (9-13)