If you're taking a GLP-1 medication like semaglutide or tirzepatide, you've probably noticed something dramatic: you're simply not hungry anymore
Lpez-Ojeda W and Hurley RA
(2014) Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in Escherichia coli FEBS Lett Isidro-Llobet A, Kenworthy MN, Mukherjee S, Kopach ME, Wegner K, Gallou F, Smith AG, Roschangar F (2019) Sustainability Challenges in Peptide Synthesis and Purification: from R&D to Production
It turns the acid down so your esophagus stops burning, but it doesn't turn it completely off leaving just enough acid to digest your food and prevent fermentation
The SUSTAIN 6 trial, in particular, demonstrated a 26% reduction in the risk of major cardiovascular events compared to the standard treatment