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It can be produced by skin cells with exposure to ultraviolet sunlight, which represents the major natural source, as vitamin D intake from diet is limited

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The crucial role of glutamine in macrophages has been emphasized through early animal experiments, which have unveiled its irreplaceable involvement in cytokine generation, including prominent players like IL-1, IL-6, and tumour necrosis factor (TNF)- [124]

Although the exact causes of Parkinsons disease are not fully understood, there is evidence that oxidative stress plays an important role in the pathogenesis of this disease

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