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For broader peptide side-effect management, see the peptide safety guide

The "LR3" modification (a substitution at position 3 and an arginine extension) reduces IGF-1 LR3's affinity for IGF-binding proteins (IGFBPs)

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The significant increase in basal respiration and maximal respiration 14 d pi indicates an enhanced activity of the electron transport chain, potentially reflecting a higher energetic demand and mitochondrial adaptation