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The FDA target action date for orforglipron is approximately April 10

The findings, published in the Journal of Extracellular Vesicles, could reshape the future of neurodegenerative therapies and may even change how scientists think about brain aging itself

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PLoS One 11(3):e0151511

Furthermore, while OA treatment did not significantly change the expression levels of FABP1 and FOXA1 relative to untreated cells, Ex-4 treatment significantly reduced the expression of these genes compared to OA treatment alone (Fig