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Neurochemical imbalance: Overstimulating synaptogenesis could disrupt the brains natural balance, potentially leading to maladaptive wiring rather than purely beneficial connections

Far in the lead is Lilly with its late-stage orforglipron, which in a June 2023 Phase II readout achieved weight loss between 9.4% and 14.7% at 36 weeks

10.1016/j.ijbiomac.2021.05.065 116

With a science-backed approach, Tirzepatide supports long-term weight loss and overall health improvement

La decisin de iniciar terapia farmacolgica debe ser individualizada, considerando la historia clnica completa, los objetivos de tratamiento, las preferencias del paciente y la relacin riesgo-beneficio