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This increased renin release is believed to be partially mediated by the beta-adrenergic system

It is the primary actin-sequestering protein in mammalian cells and has been studied for its role in cell migration, angiogenesis, and tissue repair

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According to FDA prescribing information and clinical trial data, common side effects include nausea (occurring in 1544% of patients depending on dose and indication), vomiting, diarrhea, abdominal pain, and constipation

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