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The accumulating 1 -pyrroline-5-carboxylate can then be reduced to proline by the NADP(H)-dependent enzyme pyrroline-5-carboxylate reductase (PYCR or P5CR)

doi: 10.1039/d0fo00565g Summary Keywords quercetin, cancer, 5-fluorouracil, doxorubicin, nephrotoxicity, neurotoxicity, immune cells Citation Deng H, Wei F, Han W, Li Y, Xu X, Zhang L and Zhang Y (2025) Synergistic chemotherapy and immunomodulatory effects of Quercetin in cancer: a review

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Examples of these include chitosan nanoparticles, PLGA [poly(lactic-co-glycolic acid)] nanoparticles, and lipid-based carriers such as liposomes and solid lipid nanoparticles (231, 233)

F., DiNola, A