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In an observational study that examined 15 years of medical data from 121,523 subjects who did not have AMD and 66,253 subjects who had dry AMD at baseline, all aged 50 years and older, supplemental melatonin use was associated with lower risk of developing AMD, as well as a lower risk of progressing from dry to wet AMD (Jeong 2024)

doi:10.1016/s1353-8020(02)00013-0

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