ORCs account for around 40 percent of all cancer diagnoses in the US, and the incidence of these has been rising particularly in young adults aged 25-49, shared Sonali Thosani, a medical doctor at MD Anderson Cancer Center, who was not involved in this study
In descending order, the medications used included serotonin-norepinephrine reuptake inhibitors (used by 182 patients), gabapentin (155 patients), tricyclic antidepressants (134 patients), trazodone (59 patients), pregabalin (46 patients), muscle relaxants (45 patients), montelukast (26 patients), -blockers (21 patients), aripiprazole (12 patients), histamine 1 or histamine 2 blockers (11 patients), naltrexone (8 patients), amphetamine- or methylphenidate-based stimulants (8 patients), midodrine (7 patients), fludrocortisone (6 patients), non-amphetamine stimulants (4 patients), pyridostigmine (4 patients), -blockers (1 patient), and droxidopa (1 patient)
Business models vary significantly: In-house synthesizers run their own solid-phase peptide synthesis (SPPS) reactors, lyophilizers, and QC labs
As more employees seek coverage for these drugs, companies are grappling with the impact on their health plan budgets
A review of their potential efficacy and suitability