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Skin Lightening: Reduces dark spots and hyperpigmentation

Compared with the treatment of short-acting GLP-1R agonists, LIR has a greater improvement in lowering glycated hemoglobin and fasting blood glucose

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However, the effects are dose-dependent, and optimal concentrations appear to vary by context, underscoring the need for application-specific protocols

Further, a more than two-fold increase in the duration of base rigidity at or above 60% was observed when comparing the response of individual patients to PT-141 versus placebo [15]