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In October 2023, A Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease (FLOW) trial assessing the effect of semaglutide versus placebo on the progression of renal impairment in people with T2DM and chronic kidney disease was stopped prematurely due to results of an interim analysis showing significant efficacy of semaglutide with full results due to be released in the first half of 2024 [39]

Journal Of Pharmacology And Experimental Therapeutics, 301(2), 543-550

Of the 3,183 patients enrolled in PIONEER 6, 85% were aged 50 years with established CVD and/or CKD and 15% were aged 60 years with CV risk factors only ( Table 1 )