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Summary: Retatrutide does cause nausea, which is one of the most frequently reported side effects in clinical trials, occurring most often during dose escalation and at higher doses

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Similarly, Wai et al

Issues with various parts of your heart or abnormal blood flow to your heart can affect your hearts normal rhythm

Relative Contraindications Active or recent malignancy Pregnancy or breastfeeding (no safety data) Active systemic infection Uncontrolled autoimmune disease in acute flare Concurrent use of anticoagulants without physician oversight Regulatory Status and Where to Source BPC-157 FDA Status (as of 2025) BPC-157 is not FDA-approved for any human therapeutic indication