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Carnitine and acylcarnitine can also be used as metabolic messengers to participate in the communication between tissues and coordinate energy metabolism between tissues

Given that Chac1 overexpressionmediated glutathione depletion substantially suppresses lipogenesis and mitigates MASLD/MASH progression, we asked whether Chac1 expression is regulated during normal metabolic transitions or in liver disease states

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13 : 417423 Villardita C, Smirni P, Vecchio I

The present study observed reduced expression of 25-hydroxylase enzymes and 1--hydroxylase, vitamin D receptor, and increased expression of the 24-hydroxylase enzyme in the livers of HFD-fed mice