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doi: 10.1007/s00508-015-0740-8

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Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease

2.3.2 Changes Brought by Acetylation: Stability and Membrane Permeability The acetyl group acts like a molecular protective shield, completely shielding the thiol group during transportation