did oprah use semaglutide Dr. Jen Ashton weighs in on stigma around Ozempic, weight loss drugs GLP-1s: Weight Loss Drugs, Benefits

The lawsuit follows growing concern sparked by a July 2024 Harvard study linking semaglutide drugs like Ozempic to NAION, with more evidence emerging in January 2025 and regulatory attention from European agencies

In rats self-administering fentanyl, a single dose of liraglutide, another GLP-1 drug, reduced fentanyl seeking with an efficacy that matched buprenorphine the FDA-approved drug currently considered the gold standard in treating opioid addiction

In contrast, studies of long-term administration report weaker or absent modulation of these circuits, suggesting that neural adaptations may normalize with sustained exposure or that acute effects reflect transient pharmacodynamic responses rather than stable neuroplastic changes

A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

doi: 10.1007/s42000-025-00635-5