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The two most widely used drugs work slightly differently: 1

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The peptide was synthesized using solid-phase methods and purified via reverse-phase high-performance liquid chromatography (HPLC)

For normally distributed data a mixed linear model (MLM) was used, (as laid out by IBM in their SPSS Statistics guidelines, with mice IDs as subject variable and random effects, sex and APOE genotypes as factors, and age as a covariate

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice