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A 2019 review in the Journal of Physiology noted that "IGF-1 signalling and mechanical loading converge on mTORC1 to regulate skeletal muscle protein synthesis, and the relative contribution of each remains an active area of investigation" [6]

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Eur J Clin Nutr 72, 105111.CrossRefGoogle ScholarPubMed Gandek, TB, van der Koog, L & Nagelkerke, A (2023) A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles

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