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Notably, bi-allelic MC4R mutation carriers had long-term outcomes as poor as those with bi-allelic LEPR or POMC mutations, suggesting that biallelic mutations in LMP genes generally lead to more severe impairment of surgical efficacy compared to heterozygous mutations

But the two that I'm particularly excited about really have to do with disease-modifying and saving of lives

Allow longer rest between sets (2 to 3 minutes for compound lifts)

One major flaw is that while GLP-1 patches claim to work through the skin, there is no strong evidence that their ingredients are absorbed in amounts that meaningfully affect appetite, blood sugar, or weight loss

most individuals had a BMI 40 kg/m 2