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For our Flagstaff trail runners tackling challenging elevation, Phoenix golfers braving the summer heat, or Scottsdale cyclists putting in serious miles, glutathione has become part of their performance toolkit

JAMA Netw Open 2023;6:e233398

Ebert, E

It is produced by every cell of the body, with especially high levels in the liver.* Glutathione is critical for healthy immune system function and is necessary for proper detoxification processes.* It also plays a critical role in maintaining cellular health by directly neutralizing free radicals, as well as by maintaining the activity of vitamins C and E.* Milk thistle extract and alpha lipoic acid are included as complementary ingredients

As E366 is adjacent to R365 in loop L6 of the FHA domain, a region critical for P-Thr recognition, we hypothesized that the E366G mutant could impair SNIP1 binding to P-SF3B1