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This mechanism, which is observed in breast CAFs, as well as in luminal B (BT-474) and triple-negative (MDA-MB-231) breast cancer cells, but not in HER2 (SK-BR-3) and luminal A (MCF7) tumor cells, may contribute to angiogenesis in breast tumors [126]

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This is a greatly simplified account of the process, and at least 25 proteins take part both in the transport and -oxidation aspects, some of which are organized into at least three functional subdomains, one associated with the outer mitochondrial membrane, one with the inner mitochondrial membrane and the other in the matrix

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