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Ethics declarations Ethics approval and consent to participate All experimental procedures involving animals and patients were conducted in accordance with institutional guidelines and were approved by the Laboratory Animal Center of Xian Jiaotong University (No.2022 1282) and the First Affiliated Hospital of Xian Jiaotong University (No.LLSBPJ-2023-072)

I risultati clinici che hanno sostenuto la richiesta di autorizzazione mostrano una perdita media di peso del 16,6% dopo 64 settimane di trattamento, un dato nettamente superiore rispetto al placebo

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