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A study investigated the anti-inflammatory properties of luteolin purified from the Pedilanthus tithymaloides plant

effective contraception is advised during treatment, and the medication should be discontinued at least 2 months before a planned pregnancy There is an increased risk of gallbladder disease (cholelithiasis, cholecystitis) Patients with diabetes taking insulin or sulfonylureas may have an increased risk of hypoglycaemia Patients should contact their GP or prescribing clinician if they experience: Severe or persistent gastrointestinal symptoms affecting nutritional intake Signs of dehydration Unexplained abdominal pain, particularly if severe and persistent in the upper abdomen (to exclude rare but serious complications such as pancreatitis or gallbladder disease) Difficulty maintaining adequate nutrition Patients should report any suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

Pantanowitz L, et al

Child Psychiatry Hum Dev 43:674682

K1/K10, keratin 1 and keratin 10