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Figure 1 Table 2 The strongest predictors of the level of glutathione peroxidase 1 activity were smoking status and sex

We found significant alterations in metabolite concentrations and differential effects on adenosine triphosphate (ATP) supply in neurons and astrocytes and within subcellular compartments in aged brains and identified reduced sodium/potassium adenosine triphosphatase (Na + /K + -ATPase) activity as the leading cause of impaired neuronal action potentials