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From award-winning actors to tennis legends, more and more famous people are describing how GLP-1 medicines such as Ozempic, Wegovy, Zepbound, and Mounjaro have helped their weight loss journeys

Understanding these mechanisms is crucial for developing effective treatments and preventive measures

In particular, CYP1A1 and 2E1, although playing a minor role in the overall metabolism, can be induced by PAHs making smokers more prone to severe ADRs (e.g., QT prolongation) due to increased metabolite concentrations

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Ensuring equitable access and strengthening health systems will be essential to prevent widening health disparities