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In select patientsparticularly those with obesity or metabolic syndromethis combo approach can enhance disease control, reduce flare frequency, and potentially decrease reliance on repeated antibiotic courses or escalating immunosuppressants

After that, the estimated cost per person grows faster at 17%, 11%, and 12% per year which in my view is driven by the weight-loss impact and therefore unlikely to be sustainable in the long term

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While not specifically studied for bone healing, its mechanism of reducing NF-kB activation could theoretically support the transition from inflammatory to regenerative phases