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Due to its extended activity profile and modified structure, IGF-1 LR3 is often selected for research applications that focus on long-duration signaling studies, receptor-binding dynamics, and controlled investigation of growth factorassociated biochemical pathways

With exogenous GH, in-vitro proliferation markers increased and JAK2 was activatedsuggesting a permissive/synergistic interface with GH signaling in this cell type

Birth Defects Res (2017) 109(16):124356

Peptide therapy is additive, not primary