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Venous Blood Gas (VBG) analysis identifies acid-base disturbances, such as anion gap metabolic acidosis, which may arise from lactate accumulation due to hepatic necrosis or poor tissue perfusion

doi: 10.1113/jphysiol.1991.sp018507

For some patients, what begins as loose skin may become a recurring medical problem involving itching, odour, rash or infection

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Prolonged use risks addiction and tolerance, reducing effectiveness